Vertical; perpendicular; said of the cable when the anchor is under, or nearly under, the hawse hole, and the cable is taut.
Plain; downright
Upward and downward, alternately
She looked me up and down and hinted that I could do with losing some weight.
Alternately forwards and backwards along a path
walk up and down the corridor
Staunchly, unwaveringly, obstinately
He swore up and down that he hadn't taken the money.